Title : Expression of domains for protein-protein interaction of nucleotide excision repair proteins modifies cancer cell sensitivity to platinum derivatives and genomic stability.

Pub. Date : 2014 Oct

PMID : 25115435






1 Functional Relationships(s)
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1 Finally, in particular cell models of the interaction between ERCC1 and XPF, DNA repair was decreased, as evidenced by increased phosphorylation of the histone 2AX after exposure to mitomycin C, and genomic instability was increased, as determined by comparative genomic hybridization studies. Mitomycin ERCC excision repair 1, endonuclease non-catalytic subunit Homo sapiens