Title : Evidence for the interaction of endophilin a3 with endogenous Kca2.3 channels in PC12 cells.

Pub. Date : 2014

PMID : 25096234






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Since K(Ca)2.3 specific currents could be increased in PC12 cells transfected with Endophilin A3 with DC-EBIO (30 microM), a known SK-channel activator, these data also implicate that Endophilin A3 did not significantly remove K(Ca)2.3 channels from the membrane but changed the sensitivity of the channels to Ca(2+) which could be overcome by DC-EBIO. 1-ethyl-2-benzimidazolinone SH3 domain containing GRB2 like 3, endophilin A3 Rattus norvegicus
2 Since K(Ca)2.3 specific currents could be increased in PC12 cells transfected with Endophilin A3 with DC-EBIO (30 microM), a known SK-channel activator, these data also implicate that Endophilin A3 did not significantly remove K(Ca)2.3 channels from the membrane but changed the sensitivity of the channels to Ca(2+) which could be overcome by DC-EBIO. 1-ethyl-2-benzimidazolinone SH3 domain containing GRB2 like 3, endophilin A3 Rattus norvegicus