Title : GTP is an allosteric modulator of the interaction between the guanylate-binding protein 1 and the prosurvival kinase PIM1.

Pub. Date : 2015 Feb 16

PMID : 25081641






2 Functional Relationships(s)
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1 Since GBP1 is a large GTPase which undergoes conformational changes in a nucleotide-dependent manner, we investigated the effect of GTP/GDP binding on GBP1:PIM1 interaction by using computational and biological studies. Guanosine Diphosphate guanylate binding protein 1 Homo sapiens
2 Since GBP1 is a large GTPase which undergoes conformational changes in a nucleotide-dependent manner, we investigated the effect of GTP/GDP binding on GBP1:PIM1 interaction by using computational and biological studies. Guanosine Diphosphate guanylate binding protein 1 Homo sapiens