Title : Peroxiredoxin II negatively regulates lipopolysaccharide-induced osteoclast formation and bone loss via JNK and STAT3.

Pub. Date : 2015 Jan 1

PMID : 25074339






1 Functional Relationships(s)
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1 INNOVATION: For the first time, we showed that LPS-induced ROS signaling is dependent on the coordinated mechanism of JNK and STAT3 during osteoclastogenesis, which is negatively regulated by PrxII. Reactive Oxygen Species signal transducer and activator of transcription 3 Mus musculus