Title : Attenuation of IFN-γ-induced B7-H1 expression by 15-deoxy-delta(12,14)-prostaglandin J2 via downregulation of the Jak/STAT/IRF-1 signaling pathway.

Pub. Date : 2014 Sep 1

PMID : 25072357






2 Functional Relationships(s)
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1 In this manuscript, we report that the 15-deoxy-delta(12,14)-prostaglandin J2 (15d-PGJ2), peroxisome proliferator-activated receptor gamma (PPARgamma) activator leads to the downregulation of the cancer-associated expression of B7-H1 in response to interferon-gamma (IFN-gamma) and the associated signaling cascades. 15-deoxy-delta interferon gamma Mus musculus
2 In this manuscript, we report that the 15-deoxy-delta(12,14)-prostaglandin J2 (15d-PGJ2), peroxisome proliferator-activated receptor gamma (PPARgamma) activator leads to the downregulation of the cancer-associated expression of B7-H1 in response to interferon-gamma (IFN-gamma) and the associated signaling cascades. 15-deoxy-delta interferon gamma Mus musculus