Pub. Date : 2015 Mar 15
PMID : 25066607
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Suppression of AKT expression by miR-153 produced anti-tumor activity in lung cancer. | mir-153 | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | Overexpression of miR-153 significantly inhibited AKT protein expression, which were abrogated by co-transfection of AMO-153, the specific inhibitor of miR-153. | mir-153 | AKT serine/threonine kinase 1 | Homo sapiens |
| 3 | Overexpression of miR-153 significantly inhibited AKT protein expression, which were abrogated by co-transfection of AMO-153, the specific inhibitor of miR-153. | mir-153 | AKT serine/threonine kinase 1 | Homo sapiens |
| 4 | The IC50 of miR-153 on lung cancer cells is positive correlated with the endogenous miR-153 level, while negative correlated with AKT level. | mir-153 | AKT serine/threonine kinase 1 | Homo sapiens |
| 5 | In summary, miR-153 exerted anti-tumor activity in lung cancer by targeting on AKT. | mir-153 | AKT serine/threonine kinase 1 | Homo sapiens |