Title : G226, a novel epipolythiodioxopiperazine derivative, induces autophagy and caspase-dependent apoptosis in human breast cancer cells in vitro.

Pub. Date : 2014 Aug

PMID : 25066322






1 Functional Relationships(s)
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1 G226 induced dose-dependent apoptosis of MDA-MB-231 and MCF-7 cells, accompanied by markedly increased activities of caspase-8 and caspase-3/7, which were abolished by caspase inhibitors zVAD or zIETD. benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone caspase 3 Homo sapiens