Title : Sildenafil Decreases BACE1 and Cathepsin B Levels and Reduces APP Amyloidogenic Processing in the SAMP8 Mouse.

Pub. Date : 2015 Jun

PMID : 25063079






1 Functional Relationships(s)
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1 Interestingly, sildenafil enhanced both Akt and glycogen synthase kinase-3beta (ser9) phosphorylation, which could be mediating the reduction in cathepsin B levels found in the hippocampus of sildenafil-treated SAMP8 mice. Sildenafil Citrate thymoma viral proto-oncogene 1 Mus musculus