Pub. Date : 2014 Oct
PMID : 25060694
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Liver-specific induction of Abcg5 and Abcg8 stimulates reverse cholesterol transport in response to ezetimibe treatment. | Ezetimibe | ATP binding cassette subfamily G member 8 | Homo sapiens |
| 2 | RESULTS: Our studies revealed that treatment with ezetimibe was associated with increased expression of hepatic Abcg5 and Abcg8. | Ezetimibe | ATP binding cassette subfamily G member 8 | Homo sapiens |
| 3 | CONCLUSIONS: Our study is the first to demonstrate ezetimibe treatment cooperatively stimulated macrophage-to-feces RCT by indirectly increasing liver Abcg5/Abcg8 expression in addition to its known suppression of intestinal cholesterol absorption. | Ezetimibe | ATP binding cassette subfamily G member 8 | Homo sapiens |