Title : Histone deacetylase mediates the decrease in drebrin cluster density induced by amyloid beta oligomers.

Pub. Date : 2014 Oct

PMID : 25058791






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 SAHA markedly increased the acetylation of histone proteins, and it simultaneously attenuated the ADDL-induced decrease in drebrin cluster density. Vorinostat drebrin 1 Mus musculus
2 Therefore, SAHA likely inhibits ADDL-induced drebrin loss from dendritic spines by stabilizing drebrin in these structures, rather than by increasing drebrin clusters or dendritic protrusions. Vorinostat drebrin 1 Mus musculus
3 Therefore, SAHA likely inhibits ADDL-induced drebrin loss from dendritic spines by stabilizing drebrin in these structures, rather than by increasing drebrin clusters or dendritic protrusions. Vorinostat drebrin 1 Mus musculus
4 Therefore, SAHA likely inhibits ADDL-induced drebrin loss from dendritic spines by stabilizing drebrin in these structures, rather than by increasing drebrin clusters or dendritic protrusions. Vorinostat drebrin 1 Mus musculus