Title : PGE₂ promotes apoptosis induced by cytokine deprivation through EP3 receptor and induces Bim in mouse mast cells.

Pub. Date : 2014

PMID : 25054560






3 Functional Relationships(s)
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1 PGE2 promotes apoptosis induced by cytokine deprivation through EP3 receptor and induces Bim in mouse mast cells. Dinoprostone prostaglandin E receptor 3 (subtype EP3) Mus musculus
2 We report here that PGE2 through the EP3 receptor promotes cell death of mast cells initiated by cytokine withdrawal. Dinoprostone prostaglandin E receptor 3 (subtype EP3) Mus musculus
3 Furthermore, the ability of PGE2 to limit reconstitution of tissues with cultured mast cells is lost in cell lacking the EP3 receptor. Dinoprostone prostaglandin E receptor 3 (subtype EP3) Mus musculus