Title : Arginine enhances osteoblastogenesis and inhibits adipogenesis through the regulation of Wnt and NFATc signaling in human mesenchymal stem cells.

Pub. Date : 2014 Jul 22

PMID : 25054323






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 This effect was associated with increased expression of Wnt5a, and nuclear factor of activated T-cells (NFATc), and was abrogated by antagonists of Wnt and NFATc, which indicated a role of Wnt and NFATc signaling in the switch from adipogenesis to osteoblastogenesis induced by arginine. Arginine Wnt family member 5A Homo sapiens
2 In conclusion, this is the first report of the dual action of arginine in promoting osteogenesis and inhibiting adipocyte formation through involving Wnt5a and NFATc signaling pathway. Arginine Wnt family member 5A Homo sapiens