Pub. Date : 2014 Oct
PMID : 25044948
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Docosahexaenoic acid reduces linoleic acid induced monocyte chemoattractant protein-1 expression via PPARgamma and nuclear factor-kappaB pathway in retinal pigment epithelial cells. | Docosahexaenoic Acids | C-C motif chemokine ligand 2 | Homo sapiens |
2 | SCOPE: To investigate whether docosahexaenoic acid (DHA) could inhibit linoleic acid (LA) induced monocyte chemoattractant protein (MCP)-1 expression in human retinal pigment epithelial (RPE) cells. | Docosahexaenoic Acids | C-C motif chemokine ligand 2 | Homo sapiens |
3 | SCOPE: To investigate whether docosahexaenoic acid (DHA) could inhibit linoleic acid (LA) induced monocyte chemoattractant protein (MCP)-1 expression in human retinal pigment epithelial (RPE) cells. | Docosahexaenoic Acids | C-C motif chemokine ligand 2 | Homo sapiens |
4 | DHA at 50 and 100 muM effectively inhibited LA-induced MCP-1 expression and production (p < 0.05) and NF-kappaB activation. | Docosahexaenoic Acids | C-C motif chemokine ligand 2 | Homo sapiens |
5 | CONCLUSION: DHA reduced LA-induced MCP-1 expression via a PPARgamma- and NF-kappaB-dependent pathway in ARPE-19 cells. | Docosahexaenoic Acids | C-C motif chemokine ligand 2 | Homo sapiens |