Title : [Progress of berberine for treatment of type 2 diabetes].

Pub. Date : 2014 Apr

PMID : 25039167






1 Functional Relationships(s)
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1 The mechanisms of berberine in diabetes include: improving the function of beta-cell; prompting insulin secretion and islets regeneration, lowing lipid level, regulating glucose and lipid metabolic by influence transcriptional factors expression such as PPARgamma, C/EBPalpha, SREBP-1c, LXR, having the activities of anti-oxidation and inhibiting reductase to repress oxidative stress state and regulate metabolic signal pathway. Berberine CCAAT enhancer binding protein alpha Homo sapiens