Title : Induction of apoptosis by 2,3-dehydrosilybin via a caspase-dependent pathway in human HeLa cells.

Pub. Date : 2014

PMID : 25036678






1 Functional Relationships(s)
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1 Furthermore, z-VAD-fmk (a pan-caspase inhibitor) and z-IETD-fmk (a specific caspase-8 inhibitor) abolished the DHS-induced activation of the caspase-8, -9, and -3, cleavage of PARP, the depolarization of Deltapsim, the release of cytochrome c, the cleavage of Bid, and the downregulation of Bcl-2. benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone cytochrome c, somatic Homo sapiens