Title : Negative regulation of glucose metabolism in human myotubes by supraphysiological doses of 17β-estradiol or testosterone.

Pub. Date : 2014 Sep

PMID : 25034385






2 Functional Relationships(s)
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1 Exposure of myotubes to either 17beta-estradiol or testosterone augmented phosphorylation GSK3beta(Ser9) and PKCdelta(Thr505), two negative regulators of glycogen synthesis. Testosterone protein kinase C delta Homo sapiens
2 CONCLUSION: An acute exposure to supraphysiological doses of either 17beta-estradiol or testosterone regulates glucose metabolism, possibly via PKC signaling pathways. Testosterone protein kinase C delta Homo sapiens