Title : Glucuronidation of fimasartan, a new angiotensin receptor antagonist, is mainly mediated by UGT1A3.

Pub. Date : 2015 Jan

PMID : 25034008






1 Functional Relationships(s)
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1 These findings collectively indicate that UGT1A3 is the major UGT isoform responsible for the glucuronidation of fimasartan, and this glucuronide is excreted from hepatocytes via MDR1 and BCRP. Glucuronides UDP glucuronosyltransferase family 1 member A complex locus Homo sapiens