Title : HDAC class I inhibitor, Mocetinostat, reverses cardiac fibrosis in heart failure and diminishes CD90+ cardiac myofibroblast activation.

Pub. Date : 2014

PMID : 25024745






2 Functional Relationships(s)
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1 In vitro treatment of CD90+ cells with Mocetinostat reversed myofibroblast phenotype as indicated by a decrease in alpha-Smooth muscle actin (alpha-SMA), Collagen III, and Matrix metalloproteinase-2 (MMP2). mocetinostat actin gamma 2, smooth muscle Rattus norvegicus
2 In vitro treatment of CD90+ cells with Mocetinostat reversed myofibroblast phenotype as indicated by a decrease in alpha-Smooth muscle actin (alpha-SMA), Collagen III, and Matrix metalloproteinase-2 (MMP2). mocetinostat actin gamma 2, smooth muscle Rattus norvegicus