Title : Antileukemic activity of sulforaphane in primary blasts from patients affected by myelo- and lympho-proliferative disorders and in hypoxic conditions.

Pub. Date : 2014

PMID : 25019218






1 Functional Relationships(s)
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1 As to its cytotoxic mechanism, we found that sulforaphane creates an oxidative cellular environment that induces DNA damage and Bax and p53 gene activation, which in turn helps trigger apoptosis. sulforaphane tumor protein p53 Homo sapiens