Title : Tumor suppressor p53 cooperates with SIRT6 to regulate gluconeogenesis by promoting FoxO1 nuclear exclusion.

Pub. Date : 2014 Jul 22

PMID : 25009184






1 Functional Relationships(s)
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1 In mammalian cells, tumor suppressor p53 plays critical roles in the regulation of glucose metabolism, including glycolysis and oxidative phosphorylation, but whether and how p53 also regulates gluconeogenesis is less clear. Glucose tumor protein p53 Homo sapiens