Pub. Date : 2014 Jul 8
PMID : 25006035
11 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The metal transporter ZIP13 supplies iron into the secretory pathway in Drosophila melanogaster. | Iron | Zinc/iron regulated transporter-related protein 99C | Drosophila melanogaster |
| 2 | In this study, we show Drosophila ZIP13 (Slc39a13), a presumed zinc importer, fulfills the iron effluxing role. | Iron | Zinc/iron regulated transporter-related protein 99C | Drosophila melanogaster |
| 3 | Interfering with dZIP13 expression causes iron-rescuable iron absorption defect, simultaneous iron increase in the cytosol and decrease in the secretory compartments, failure of ferritin iron loading, and abnormal collagen secretion. | Iron | Zinc/iron regulated transporter-related protein 99C | Drosophila melanogaster |
| 4 | Interfering with dZIP13 expression causes iron-rescuable iron absorption defect, simultaneous iron increase in the cytosol and decrease in the secretory compartments, failure of ferritin iron loading, and abnormal collagen secretion. | Iron | Zinc/iron regulated transporter-related protein 99C | Drosophila melanogaster |
| 5 | Interfering with dZIP13 expression causes iron-rescuable iron absorption defect, simultaneous iron increase in the cytosol and decrease in the secretory compartments, failure of ferritin iron loading, and abnormal collagen secretion. | Iron | Zinc/iron regulated transporter-related protein 99C | Drosophila melanogaster |
| 6 | Interfering with dZIP13 expression causes iron-rescuable iron absorption defect, simultaneous iron increase in the cytosol and decrease in the secretory compartments, failure of ferritin iron loading, and abnormal collagen secretion. | Iron | Zinc/iron regulated transporter-related protein 99C | Drosophila melanogaster |
| 7 | dZIP13 expression in E. coli confers upon the host iron-dependent growth and iron resistance. | Iron | Zinc/iron regulated transporter-related protein 99C | Drosophila melanogaster |
| 8 | dZIP13 expression in E. coli confers upon the host iron-dependent growth and iron resistance. | Iron | Zinc/iron regulated transporter-related protein 99C | Drosophila melanogaster |
| 9 | Importantly, time-coursed transport assays using an iron isotope indicated a potent iron exporting activity of dZIP13. | Iron | Zinc/iron regulated transporter-related protein 99C | Drosophila melanogaster |
| 10 | Importantly, time-coursed transport assays using an iron isotope indicated a potent iron exporting activity of dZIP13. | Iron | Zinc/iron regulated transporter-related protein 99C | Drosophila melanogaster |
| 11 | The identification of dZIP13 as an iron transporter suggests that the spondylocheiro dysplastic form of Ehlers-Danlos syndrome, in which hZIP13 is defective, is likely due to a failure of iron delivery to the secretory compartments. | Iron | Zinc/iron regulated transporter-related protein 99C | Drosophila melanogaster |