Title : γH2AX and Chk1 phosphorylation as predictive pharmacodynamic biomarkers of Chk1 inhibitor-chemotherapy combination treatments.

Pub. Date : 2014 Jul 4

PMID : 24996846






1 Functional Relationships(s)
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1 Induction of gammaH2AX levels was chemotherapeutic dependent and correlated closely with potentiation of gemcitabine and camptothecin in p53 mutant colon cancer cells. Camptothecin tumor protein p53 Homo sapiens