Title : PCSK9 and LDLR The Yin-Yang in the Cellular Uptake of Cholesterol.

Pub. Date : 2014 Jul 1

PMID : 24993279






1 Functional Relationships(s)
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1 The goal of this research area is to reduce the incidence of cardiovascular events beyond statins; the strategy is to mimic the state of PCSK9 "loss" of function by tactics as oligonucleotide therapies targeting PCSK9 mRNA and/or biological therapies with human monoclonal antibodies targeting PCSK9. Oligonucleotides proprotein convertase subtilisin/kexin type 9 Homo sapiens