Title : Regulation of MHC expression in vivo. II. IFN-alpha/beta inducers and recombinant IFN-alpha modulate MHC antigen expression in mouse tissues.

Pub. Date : 1989 Jun 15

PMID : 2498428






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 polyI:C increased renal class I MHC in nude mice and mice with severe combined immunodeficiency, and in mice treated with cyclosporine or mAb against IFN-gamma. Cyclosporine interferon gamma Mus musculus
2 However, a potent T cell stimulus, allogeneic ascites tumor cells, induced markedly different MHC changes, with massive and sustained increases in class I and II, presumably due to IFN-gamma release, which was inhibited by cyclosporine or by mAb against IFN-gamma. Cyclosporine interferon gamma Mus musculus