Pub. Date : 2014 Jun
PMID : 24980758
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Tamoxifen inhibited MCF7 cells co-treated with EGF or oestrogen, and enhanced the inhibitory effect of TGFbeta in MDA-MB-231 cells. | Tamoxifen | transforming growth factor beta 1 | Homo sapiens |
| 2 | Meta-analysis of clinical gene expression studies confirmed several of these points, showing enhanced TGFbeta and EGF expression in Tamoxifen-treated patients to correlate with decreased tumour size and grade respectively, and combined TGFbeta-EGF expression to decrease the risk of metastasis. | Tamoxifen | transforming growth factor beta 1 | Homo sapiens |