Title : Complement C3a binding to its receptor as a negative modulator of Th2 response in liver injury in trichloroethylene-sensitized mice.

Pub. Date : 2014 Aug 17

PMID : 24974766






2 Functional Relationships(s)
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Protein Name
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1 A mouse model of skin sensitization was induced by TCE in the presence and absence of the C3aR antagonist SB 290157. SB 290157 complement component 3a receptor 1 Mus musculus
2 Pretreatment with SB 290157 resulted in more inflammatory infiltration in the liver, higher levels of AST, reduced C3aR expression on Kupffer cells, and decreased IL-4 levels while IFN-gamma remained unchanged. SB 290157 complement component 3a receptor 1 Mus musculus