Title : PCB153, TCDD and estradiol compromise the benzo[a]pyrene-induced p53-response via FoxO3a.

Pub. Date : 2014 Aug 5

PMID : 24954032






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 PCB153, TCDD and estradiol compromise the benzo[a]pyrene-induced p53-response via FoxO3a. Estradiol tumor protein p53 Homo sapiens
2 We have studied the effect of TCDD, PCB153 and estradiol on p53 signaling induced by PAHs. Estradiol tumor protein p53 Homo sapiens
3 Our data indicate interplay between p53, FoxO3a and 14-3-3 leading to an attenuated BaP induced apoptosis in cells co-exposed to TCDD, PCB 153 or estradiol. Estradiol tumor protein p53 Homo sapiens