Title : Conformational dynamics of human FXR-LBD ligand interactions studied by hydrogen/deuterium exchange mass spectrometry: insights into the antagonism of the hypolipidemic agent Z-guggulsterone.

Pub. Date : 2014 Sep

PMID : 24953769






2 Functional Relationships(s)
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1 Conformational dynamics of human FXR-LBD ligand interactions studied by hydrogen/deuterium exchange mass spectrometry: insights into the antagonism of the hypolipidemic agent Z-guggulsterone. pregna-4,17-diene-3,16-dione nuclear receptor subfamily 1 group H member 4 Homo sapiens
2 A comparison of the HDX profiles of their ligand-bound FXR-LBD complexes revealed a unique mode of interaction for GG. pregna-4,17-diene-3,16-dione nuclear receptor subfamily 1 group H member 4 Homo sapiens