Title : Micronuclei in bone marrow and liver in relation to hepatic metabolism and antioxidant response due to coexposure to chloroform, dichloromethane, and toluene in the rat model.

Pub. Date : 2014

PMID : 24949447






2 Functional Relationships(s)
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Protein Name
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1 Chloroform, dichloromethane, and toluene are primarily metabolized in liver by CYP2E1, producing reactive electrophilic metabolites, and may also produce oxidative stress via the uncoupled CYP2E1 catalytic cycle. Toluene cytochrome P450, family 2, subfamily e, polypeptide 1 Rattus norvegicus
2 Chloroform, dichloromethane, and toluene are primarily metabolized in liver by CYP2E1, producing reactive electrophilic metabolites, and may also produce oxidative stress via the uncoupled CYP2E1 catalytic cycle. Toluene cytochrome P450, family 2, subfamily e, polypeptide 1 Rattus norvegicus