Pub. Date : 2014 Nov
PMID : 24947350
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | SIRT1 mediates the effect of GLP-1 receptor agonist exenatide on ameliorating hepatic steatosis. | Exenatide | glucagon-like peptide 1 receptor | Mus musculus |
| 2 | Here, we speculate that SIRT1 might mediate the effect of the GLP-1 receptor agonist exenatide (exendin-4) on ameliorating hepatic steatosis. | Exenatide | glucagon-like peptide 1 receptor | Mus musculus |
| 3 | Here, we speculate that SIRT1 might mediate the effect of the GLP-1 receptor agonist exenatide (exendin-4) on ameliorating hepatic steatosis. | Exenatide | glucagon-like peptide 1 receptor | Mus musculus |
| 4 | Our data demonstrate that SIRT1 mediates the effect of exenatide on ameliorating hepatic steatosis, suggesting the GLP-1 receptor agonist could serve as a potential drug for nonalcoholic fatty liver disease (NAFLD), especially in type 2 diabetes combined with NAFLD, and SIRT1 could be a therapeutic target of NAFLD. | Exenatide | glucagon-like peptide 1 receptor | Mus musculus |