Title : Hypothalamic-pituitary-adrenal axis response to oral naltrexone in alcoholics during early withdrawal.

Pub. Date : 2014 Jul

PMID : 24936803






4 Functional Relationships(s)
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1 METHODS: Cortisol and adrenocorticotrophic hormone (ACTH) responses to naltrexone were measured in alcohol-dependent males (n=23) and in healthy males (n=20). Naltrexone proopiomelanocortin Homo sapiens
2 RESULTS: Naltrexone administration resulted in a significant ACTH response in the patients while cortisol and ACTH responses were found to be significant in the controls. Naltrexone proopiomelanocortin Homo sapiens
3 ACTH level changes as a response to naltrexone in the patients were lower than that in the controls. Naltrexone proopiomelanocortin Homo sapiens
4 DISCUSSION: The study revealed blunted cortisol and attenuated ACTH responses to naltrexone in early alcohol withdrawal. Naltrexone proopiomelanocortin Homo sapiens