Title : Genetic inhibition of the atypical kinase Wee1 selectively drives apoptosis of p53 inactive tumor cells.

Pub. Date : 2014 Jun 13

PMID : 24927813






1 Functional Relationships(s)
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1 In total, targeting the atypical kinase Wee1 with an siRNA-based therapeutic or a selective ATP competitive small molecule inhibitor would be a feasible approach to targeting p53 inactive tumors in the clinic. Adenosine Triphosphate tumor protein p53 Homo sapiens