Pub. Date : 2015 Mar
PMID : 24898668
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Here we analyzed the activity and mechanism of a p53 reactivator, ellipticine, in a cellular model of cutaneous T-cell lymphoma (CTCL), a disease that is progressive, chemoresistant and refractory to treatment. | ellipticine | tumor protein p53 | Homo sapiens |
| 2 | Ellipticine caused apoptosis in MyLa2000 and SeAx and restored the transcriptional activity of (G245S)p53 in SeAx. | ellipticine | tumor protein p53 | Homo sapiens |