Title : Siglec-E promotes β2-integrin-dependent NADPH oxidase activation to suppress neutrophil recruitment to the lung.

Pub. Date : 2014 Jul 18

PMID : 24895121






2 Functional Relationships(s)
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Protein Name
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1 Siglec-E is a sialic acid-binding Ig-like lectin expressed on murine myeloid cells. N-Acetylneuraminic Acid sialic acid binding Ig-like lectin E Mus musculus
2 Here, we demonstrate that siglec-E promoted neutrophil production of reactive oxygen species (ROS) following CD11b beta2-integrin ligation with fibrinogen in a sialic acid-dependent manner, but it had no effect on ROS triggered by a variety of other stimulants. N-Acetylneuraminic Acid sialic acid binding Ig-like lectin E Mus musculus