Title : Sophoricoside fails the embryo implantation by compromising the uterine endometrial receptivity at implantation "window" of pregnant mice.

Pub. Date : 2014 Aug 5

PMID : 24877640






2 Functional Relationships(s)
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1 When the administrated dose of SOPH was 600 mg/kg per day, great changes were observed in the exposed uterine morphology and up-regulated progesterone receptor (PR) and down-regulated estrogen receptor alpha (ERalpha), E-cadherin, matrix metalloproteinase-2 (MMP-2) and integrin beta3 were also found in SOPH-exposed uterine. sophoricoside progesterone receptor Mus musculus
2 When the administrated dose of SOPH was 600 mg/kg per day, great changes were observed in the exposed uterine morphology and up-regulated progesterone receptor (PR) and down-regulated estrogen receptor alpha (ERalpha), E-cadherin, matrix metalloproteinase-2 (MMP-2) and integrin beta3 were also found in SOPH-exposed uterine. sophoricoside progesterone receptor Mus musculus