Pub. Date : 2014
PMID : 24870784
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Rice bran phytic acid induced apoptosis through regulation of Bcl-2/Bax and p53 genes in HepG2 human hepatocellular carcinoma cells. | Phytic Acid | tumor protein p53 | Homo sapiens |
| 2 | PA treated HepG2 cells showed up-regulation of p53, Bax, Caspase-3 and -9, and down- regulation of Bcl-2 gene (p <= 0.01). | Phytic Acid | tumor protein p53 | Homo sapiens |
| 3 | At the IC50 (2.49 mM) of PA, the p53, Bax, Caspase-3 and-9 genes were up- regulated by 6.03, 7.37, 19.7 and 14.5 fold respectively. | Phytic Acid | tumor protein p53 | Homo sapiens |