Title : Age-related changes in tissue macrophages precede cardiac functional impairment.

Pub. Date : 2014 May

PMID : 24861132






1 Functional Relationships(s)
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1 Gene expression profiles of the two Mrc1+ subsets also reveal that Mrc1+GFP(lo) cTMs have a decreased number of immune response genes (Cx3cr1, Lpar6, CD9, Cxcr4, Itga6 and Tgfbetar1), and an increased number of fibrogenic genes (Ltc4s, Retnla, Fgfr1, Mmp9 and Ccl24), consistent with a potential role for cTMs in cardiac fibrosis. CTMS chemokine (C-C motif) ligand 24 Mus musculus