Pub. Date : 2014
PMID : 24858807
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Exposure to chronic hypoxia up-regulated the gene expression of the KCa2.3 channel by twofold in wild type mice and increased by 2.5-fold the relaxation evoked by the KCa2.3 and KCa3.1 channel activator NS309, whereas the acetylcholine-induced relaxation - sensitive to the combination of KCa2.3 and KCa3.1 channel blockers, apamin and charybdotoxin - was reduced by 2.5-fold in chronic hypoxic mice of either genotype. | Acetylcholine | potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 | Mus musculus |