Title : Regulation of rotenone-induced microglial activation by 5-lipoxygenase and cysteinyl leukotriene receptor 1.

Pub. Date : 2014 Jul 14

PMID : 24858057






2 Functional Relationships(s)
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1 We have recently reported that 5-LOX and CysLT(1)R mediated PC12 cell injury induced by high concentrations of rotenone (0.3-10 muM), which was reduced by the selective 5-LOX inhibitor zileuton and CysLT(1)R antagonist montelukast. montelukast arachidonate 5-lipoxygenase Rattus norvegicus
2 We have recently reported that 5-LOX and CysLT(1)R mediated PC12 cell injury induced by high concentrations of rotenone (0.3-10 muM), which was reduced by the selective 5-LOX inhibitor zileuton and CysLT(1)R antagonist montelukast. montelukast arachidonate 5-lipoxygenase Rattus norvegicus