Title : Extracellular UDP-glucose activates P2Y14 Receptor and Induces Signal Transducer and Activator of Transcription 3 (STAT3) Tyr705 phosphorylation and binding to hyaluronan synthase 2 (HAS2) promoter, stimulating hyaluronan synthesis of keratinocytes.

Pub. Date : 2014 Jun 27

PMID : 24847057






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 We found that small amounts of UDP-sugars were released from keratinocytes and that UDP-glucose (UDP-Glc) added into keratinocyte cultures induced a specific, rapid induction of hyaluronan synthase 2 (HAS2), and an increase of hyaluronan synthesis. Hyaluronic Acid hyaluronan synthase 2 Homo sapiens