Title : Low ATM protein expression and depletion of p53 correlates with olaparib sensitivity in gastric cancer cell lines.

Pub. Date : 2014

PMID : 24841718






1 Functional Relationships(s)
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1 Moreover, reducing ATM kinase activity using a small-molecule inhibitor (KU55933) or shRNA-mediated depletion of ATM protein enhanced olaparib sensitivity in gastric cancer cell lines with depletion or inactivation of p53. 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one ATM serine/threonine kinase Homo sapiens