Pub. Date : 2014 Aug
PMID : 24835079
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | This study investigated whether DHA prevents a palmitate-induced increase in proteolysis by restoring Akt/FoxO signaling. | Docosahexaenoic Acids | AKT serine/threonine kinase 1 | Homo sapiens |
2 | DHA attenuated the effects of palmitate on Akt activation, FoxO3 localization and atrogene mRNAs. | Docosahexaenoic Acids | AKT serine/threonine kinase 1 | Homo sapiens |
3 | These data indicate that palmitate induces myotube atrophy, at least in part, by activating multiple proteolytic systems and that DHA counters the catabolic effects of palmitate by restoring Akt/FoxO signaling. | Docosahexaenoic Acids | AKT serine/threonine kinase 1 | Homo sapiens |