Title : Polymorphisms of uridine glucuronosyltransferase gene and irinotecan toxicity: low dose does not protect from toxicity.

Pub. Date : 2014

PMID : 24834123






3 Functional Relationships(s)
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Protein Name
Organism
1 Uridine glucuronosyltransferase (UGT) gene polymorphisms have been linked to irinotecan toxicity. Irinotecan UDP glucuronosyltransferase family 1 member A complex locus Homo sapiens
2 Uridine glucuronosyltransferase (UGT) gene polymorphisms have been linked to irinotecan toxicity. Irinotecan UDP glucuronosyltransferase family 1 member A complex locus Homo sapiens
3 To conclude, UGT polymorphisms play a role in the toxicity of irinotecan, even if the drug is administered in low doses. Irinotecan UDP glucuronosyltransferase family 1 member A complex locus Homo sapiens