Pub. Date : 2014 May 30
PMID : 24833108
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Decitabine augmented RAD51 foci formation (marker for homologous recombination (HR)) and/or 53BP1 foci formation (marker for non-homologous end joining (NHEJ)). | Decitabine | RAD51 recombinase | Homo sapiens |
| 2 | Interestingly, JNJ-26481585 negatively affected basal or decitabine-induced RAD51 foci formation. | Decitabine | RAD51 recombinase | Homo sapiens |
| 3 | Finally, B02 (RAD51 inhibitor) enhanced decitabine-mediated apoptosis. | Decitabine | RAD51 recombinase | Homo sapiens |
| 4 | JNJ-26481585 negatively affects RAD51 foci formation, thereby providing an additional explanation for the combinatory effect between decitabine and JNJ-26481585. | Decitabine | RAD51 recombinase | Homo sapiens |