Title : Interactions of endosulfan and methoxychlor involving CYP3A4 and CYP2B6 in human HepaRG cells.

Pub. Date : 2014 Aug

PMID : 24832206






1 Functional Relationships(s)
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1 In the present work, we searched for interactions between endosulfan and methoxychlor, two organochlorine pesticides whose major routes of metabolism involve CAR- and PXR-regulated CYP3A4 and CYP2B6, and whose mechanisms of action in humans remain poorly understood. Hydrocarbons, Chlorinated nuclear receptor subfamily 1 group I member 3 Homo sapiens