Title : Modifications of gamma-glutamyl transpeptidase activity in duodenal mucosa of rats treated with different antiulcer drugs.

Pub. Date : 1989 Jun

PMID : 2482713






3 Functional Relationships(s)
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1 The activity of gamma-glutamyl transpeptidase (gamma-GT) in duodenal mucosa both in healthy rats and in rats experimentally ulcerated with indomethacin increases significantly after oral administration of pirenzepine as well as ranitidine but not after oral administration of sucralphate. Ranitidine gamma-glutamyltransferase 1 Rattus norvegicus
2 The activity of gamma-glutamyl transpeptidase (gamma-GT) in duodenal mucosa both in healthy rats and in rats experimentally ulcerated with indomethacin increases significantly after oral administration of pirenzepine as well as ranitidine but not after oral administration of sucralphate. Ranitidine gamma-glutamyltransferase 1 Rattus norvegicus
3 These increase in gamma-GT activity may contribute to the cytoprotective effects already described for pirenzepine and ranitidine. Ranitidine gamma-glutamyltransferase 1 Rattus norvegicus