Title : Small molecule kinase inhibitors alleviate different molecular features of myotonic dystrophy type 1.

Pub. Date : 2014

PMID : 24824895






1 Functional Relationships(s)
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1 Herein, we present results of culturing of human DM1 myoblasts and fibroblasts with two small-molecule ATP-binding site-specific kinase inhibitors, C16 and C51, which resulted in the alleviation of the dominant-negative effects of CUG repeat expansion. 3-Carboxyumbelliferyl beta-D-galactopyranoside DM1 protein kinase Homo sapiens