Title : Variability in the effects of nicotine on different regions of the brain: changes in the concentration of superoxide dismutase isoforms.

Pub. Date : 2014

PMID : 24807738






1 Functional Relationships(s)
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1 Previous studies have shown that rats subjected to subchronic treatment with nicotine experience changes in COX-2 (a marker of pro-inflammatory systems) and accumulate lipid hydroperoxides (a marker of oxidative stress) in the CNS (CNSMC, 2010; 10:180-206) (hippocampus, frontoparietal cortex and cerebellar cortex). Nicotine cytochrome c oxidase II, mitochondrial Rattus norvegicus