Title : Effect of inhibitors of N-linked oligosaccharide processing on the cell surface expression of a melanoma integrin.

Pub. Date : 1989 Sep

PMID : 2480355






2 Functional Relationships(s)
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1 The role of trimming and processing of N-linked oligosaccharides on the cell surface expression of the melanoma vitronectin receptor, a member of the integrin family of cell adhesion receptors, was examined by using specific glucosidase and mannosidase inhibitors. n-linked oligosaccharides vitronectin Homo sapiens
2 Conversely, the vitronectin receptor synthesized in the presence of the mannosidase I and II inhibitors, 1-deoxymannojirimycin and swainsonine, was transported normally to the cell surface with its alpha chain N-linked oligosaccharides in an endoglycosidase H-sensitive form. n-linked oligosaccharides vitronectin Homo sapiens