Title : Role of G protein-coupled estrogen receptor 1 in modulating transforming growth factor-β stimulated mesangial cell extracellular matrix synthesis and migration.

Pub. Date : 2014 Jun 25

PMID : 24793639






1 Functional Relationships(s)
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1 As a result, 17beta-estradiol and Fulvestrant inhibit TGF-beta1-induced type IV collagen and fibronectin expression in a dose-dependent manner, by suppressing acute Smad2/3 phosphorylation and Smad4 complex formation. Estradiol transforming growth factor beta 1 Homo sapiens